Faculty Mentors

Research Focus: Neural substrates underlying motivation and reward

Research Focus: Means by which the cytoskeleton controls cell division, wound healing, and endocytosis.

Research Focus: We study how the development of the cerebral cortex is altered in neurodevelopmental disorders characterized by intellectual disability, particularly Down syndrome. We use human stem cells and post-mortem brain tissue to identify cell…

Research Focus: We study the developmental biology of the islet of Langerhans in the pancreas, and how they are affected in diabetes

Research Focus: The Brown Lab focuses on exploring the nexus of pluripotent stem cell (PSC) biology and immunology. We are currently investigating the mechanisms underpinning the immune response to autologous and allogeneic PSC-derived cell therapies.…

Research Focus: Coordination of growth with nutrient availability by TARGET OF RAPAMYCIN in plant models, using approaches from genetics, genomics, cell and molecular biology, and physiology

Research Focus: Molecular biology of learning and memory, and the genetic mechanisms underlying neurological disorders.

Research Focus: We study mechanisms of horizontal gene transfer and interbacterial competition, using classical microbiology, fluorescence microscopy, and bioinformatic methods.

Research Focus: The Cavagnero group focuses on understanding the structural biology and mechanism of protein folding and aggregation in the cell, including the role of molecular chaperones and the ribosome in cell biology and disease.

Research Focus: We utilize nonhuman primate models to explore the impact of nutrition and metabolism on health across the aging continuum.

Research Focus: Mosquitoes, insect-microbe interactions, vector biology

Research Focus: We study molecular and cellular mechanisms of chronic pain, visceral pain, and peripheral neuropathy. We also contribute to comparative neurodegeneration research in studies with patient tissues (including veterinary patients).

Research Focus: We are interested in the role of the cytoskeleton in neuronal development and adult plasticity.

Research Focus: Tissue stem cell lineages sense and respond to the external and systemic environments. Our lab investigates the physiological, cellular and molecular in vivo mechanisms involved in this complex process using the powerful Drosophila oogenesis model.

Research Focus: We study how metabolism in immune cells (mainly macrophages and neutrophils) is dynamically rewired during immune response, and how metabolism supports and regulates immune functions.

Research Focus: We study how viruses hijack infected cells, take control of cellular gene expression, and escape anti-viral responses, with a particular focus on the human pathogens influenza A virus and Kaposi’s sarcoma-associated herpesvirus.

Research Focus: We study genotype-phenotype-environment relationships, using yeast stress responses and human rare diseases as model systems.

Research We study how multidrug efflux pumps contribute to bacterial resistance or susceptibility to toxic compounds. We investigate the molecular structure and motion of these pumps to develop mechanistic models that we test in liposomes…

Research Focus: The role of serotonin/SSRIs on peripartal reproductive and mammary gland function, as well as offspring outcomes.

Research Focus: We study the mechanisms regulating synaptic connectivity in the developing and diseased retina.

Research Focus: We study molecular mechanisms that control fungal development and sporulation, elucidating the basic properties of spores that allow them to be infectious particles, and developing interventions to prevent and/or treat severe fungal diseases.

Research Focus: In the Huttenlocher laboratory we strive to discover new cell biological mechanisms during inflammation and its resolution, and their implications to human disease

Research Focus: Our research program is aimed at understanding the molecular mechanisms causing age-dependent abnormalities and its association with age-related diseases. Our studies have shown that mouse models showing accelerated aging phenotypes provide powerful tools…

Research Focus: We study female and male gonad development to understand the fetal basis of sex-specific adult diseases in reproductive endocrinology.

Research focus Improving outcomes for cancer patients by increasing the response to radiation and treating toxicities of treatment.

Research Focus: We study the host/pathogen interactions of protozoan parasites, including Toxoplasma gondii, the causative agent of toxoplasmosis, and T. gondii‘s diarrhea-causing cousins Cryptosporidium parvum and Entamoeba histolytica.

Research Focus: We use tissue engineering and systems biology methods to understand the role of the microenvironment in ovarian cancer metastasis.

Research Focus: In the Majumder Lab, we study how viruses localize to host nuclear sites to establish viral replication centers. We are particularly interested in how viral genome localization depends on the host cell’s DNA…

Research Focus: We ask how beneficial bacteria are reproducibly acquired from the environment by animal hosts, focusing on the interaction between Hawaiian bobtail squid and luminescent Vibrio fischeri bacteria. We combine bacterial genetics, imaging, and…

Research Focus: We take a bioengineering approach to answering fundamental and medical questions about biological signal processing with an emphasis on model and pathogenic yeasts.

Research Focus: Central nervous system regeneration in adult mammals through both neuronal replacement with endogenous stem cells making newborn neurons in the brain (adult neurogenesis), and axonal regeneration following injury

Research Interests: We use mouse models to understand how the host microbiome influences tissue immunity, and how epithelial cells in the gastrointestinal tract talk to immune cells.

Research Focus: We use synthetic biology to implement metabolic engineering strategies in industrial microbes to convert available low-cost feedstocks, including environmental wastes, into higher-value commodities including biofuels, commodity chemicals, natural products, pharmaceuticals, and proteins.

Research Focus: We study molecular and cellular mechanisms involved in urologic diseases for the development of new therapies

Research Focus: We study the neural computations supporting 3D vision, multisensory integration, and the neurocomputational basis of autism.

Research Focus: Our lab studies Staphylococcus aureus pathogenesis with a focus on infective endocarditis and sepsis and the specific contribution of superantigens and cytolysins to disease.

Research Focus: Our goal is to understand how blood flow is regulated in health and disease. We focus on how obesity or pre-diabetes impacts blood flow regulation, in both skeletal muscle and brain tissue.

Research Focus: We study HIV-host cell interactions using live cell imaging and biochemical approaches.

Research Focus: We functionally characterize lipids in the plasma associated with cardiovascular disease using mass spectrometry based lipidomics

Research Focus: We study early stages of neural processing in the visual system with a focus on synapse and circuit function in the retina.

Research Focus: We study a mysterious organelle called the midbody remnant (MBR) that is necessary for cell fate in stem cells and is dysregulated in cancer.

Research Focus: Our lab aims to identify and characterize the molecular and cellular mechanisms that govern human brain development and evolution, and to apply that knowledge towards understanding neurodevelopmental and psychiatric disorders.

Research Focus: In the Tamplin lab, we study the basic biology of hematopoietic stem cells (HSC) and their microenvironment. These stem cells are clinically important as a curative treatment for many blood cancers and diseases.…

Research Focus: We study the toxicology, pharmacology, physiology, microbiology, neurobiology and genetics of benign urinary disease (our research spans diverse interests, offering something for everyone).

Research Focus: We use fruit flies (Drosophila) to study the genetics and molecular biology of traumatic brain injury.

Research Focus: Regulation of chromosome segregation during mitosis. Impact of chromosome missegregation on tumors.

Research Focus: My laboratory uses mouse developmental genetics to explore the function of Hox-expressing stem and progenitor cells in muscle, skeleton and lung. We have generated many new mouse models including reporters, lineage-trace models, conditional…

Research Focus: We study pharmaceutical and dietary interventions for the treatment of fragile X syndrome, a rare developmental disorder on the autism spectrum.